| Intro | English Catholic priest |
| Is | Priest |
| From | United Kingdom |
| Type | Religion |
| Gender | male |
James Hughes may refer to:
Sports
- James Hughes (rugby union) (1886–1943), Australian rugby union player
- James Hughes (ice hockey) (1906–1983), Canadian professional ice hockey player
- James Hughes (footballer) (1885–1948), English footballer who played for Liverpool F.C.
- Jay Hughes (1874–1924), also known as Jim Hughes, American Major League Baseball pitcher, who played four seasons from 1898 to 1902
- Jim Hughes (1950s pitcher) (1923–2001), American baseball pitcher
- Jim Hughes (1970s pitcher) (born 1951), American baseball pitcher
- James Hughes (boxer) (1965–1995), American flyweight boxer
- Jimmy Hughes (footballer) (1909–1966), English footballer
- Jamie Hughes (born 1977), former professional English footballer
- Jim Hughes (Canadian football) (born 1933), former Canadian football player
- Jim Hughes (footballer, born 1960), Scottish footballer
- Jim Hughes (footballer, born 1965), Scottish footballer
Politicians
- James Hughes (British politician) (died 1845), British Member of Parliament for Grantham
- James B. Hughes (1805–1873), American newspaper publisher, state legislator for Ohio
- James Madison Hughes (1809–1861), U.S. Representative from Missouri
- James Hughes (representative) (1823–1873), U.S. Representative from Indiana
- James Joseph Hughes (1856–1941), Canadian Senator and Member of Parliament
- James A. Hughes (1861–1930), U.S. Representative from West Virginia
- James H. Hughes (1867–1953), American lawyer and politician, U.S. Senator from Delaware
- James F. Hughes (1883–1940), U.S. Representative from Wisconsin
- James Hughes (Irish politician) (died 1948), Irish Fine Gael politician
- Jim Hughes (politician) (born 1964), Ohio politician
Others
- James Hughes (bishop) (1894–1979), Anglican bishop
- Jimmy Hughes (singer) (born 1938), American soul singer
- Jimmy Hughes (British musician) (born 1958), British punk rock/New Wave bassist
- James Hughes (sociologist) (born 1961), American sociologist and bioethicist
- James D. Hughes (born 1922), retired American Air Force lieutenant general
- Jim Hughes (academic), professor of comparative politics at the London School of Economics
- Jimmy Hughes, Rookie Cop, American television show (1953)